Young patient receives HD therapy sitting in a chair with a clinician beside her

Polyflux H and Polyflux L Dialyser Series

Vantive Polyflux dialysers are offered in a high-flux series — Polyflux H — and a low-flux series — Polyflux L. Both series promote biocompatibility and deliver proven performance.

Polyflux H: For effective convective therapies and regular high-flux HD

The Polyflux H dialyser series is a range of dialysers that effectively support the delivery of high-volume convective therapies1 (HDF or HF mode), as well as regular high-flux haemodialysis. The series is proven to deliver biocompatibility2 and endotoxin retention3 with consistent performance. The series helps control the loss of essential proteins such as albumin,4 which is particularly challenging at high flows and transmembrane pressures. Polyflux H dialysers are aimed at delivering stable and high-performing convective treatments, supporting a consistent reach of high volumes of substitution fluid.

Polyflux H Dialysers

Benefits of the Polyflux H dialyser series

  • Promoting biocompatibility2,3 with convective volumes in mind

  • 3-layer Polyamix membrane has been designed to optimise the combination of high diffusive and convective transport rates

  • Narrow pore size allows for effective permeability to small and conventional middle molecules1

  • Steam sterilised from the inside-out, promoting biocompatibility and preventing exposure to manufacturing residues and dangerous chemicals5,6

Learn more about the Polyflux H dialyser series

Read more about how the Polyflux H dialyser series contributes to Vantive’s larger dialyser portfolio by providing safe, effective  and biocompatible convective therapies to patients.

Download the datasheet

Polyflux L: A proven balance of quality and performance in low flux

The Polyflux L dialyser series is a range of dialysers specialised for low-flux haemodialysis treatments, featuring a distinctive membrane that acts as an effective barrier to potential fluid contaminants, while still delivering high performance.7 

Polyflux L dialysers

Benefits of the Polyflux L dialyser series

  • Promoting biocompatibility3,5 with high performance in mind

  • Distinctive membrane design that prevents endotoxins from crossing the dialyser membrane2,3

  • Steam sterilised inside-out, preventing exposure to chemicals such as ethylene oxide and manufacturing residues5,6

  • Exclusive 3-layered membrane structure, designed to support a stable high performance over time7

Learn more about the Polyflux L dialyser series

Read more about how the Polyflux L dialyser series contributes to Vantive’s larger dialyser portfolio by providing biocompatible, yet effective low-flux therapies to patients.

Download datasheet

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Vantive, Polyamix and Polyflux are trademarks of Vantive Health LLC or its affiliates.

References

  1. Maduell F, Moreso F, Pons M, et al. High-efficiency postdilution online hemodiafiltration reduces all-cause mortality in hemodialysis patients [published correction appears in J Am Soc Nephrol. 2014 May;25(5):1130]. J Am Soc Nephrol. 2013;24(3):487-497.

  2. Schepers E, Glorieux G, Eloot S, et al. Assessment of the association between increasing membrane pore size and endotoxin permeability using a novel experimental dialysis simulation set-up. BMC Nephrol. 2018;19(1):1.

  3. Ronco C, Crepaldi C, Brendolan A, et al. Evolution of synthetic membranes for blood purification: the case of the Polyflux family. Nephrol Dial Transplant. 2003;18 Suppl 7:vii10-vii55.

  4. Potier J, Queffeulou G, Bouet J. Are all dialyzers compatible with the convective volumes suggested for postdilution online hemodiafiltration?. Int J Artif Organs. 2016;39(9):460-470.

  5. Golli-Bennour EE, Kouidhi B, Dey M, et al. Cytotoxic effects exerted by polyarylsulfone dialyser membranes depend on different sterilization processes. Int Urol Nephrol. 2011;43(2):483-490. 

  6. Purello D'Ambrosio F, Savica V, Gangemi S, et al. Ethylene oxide allergy in dialysis patients. Nephrol Dial Transplant. 1997;12(7):1461-1463. 

  7. Vantive Health LLC. Polyflux L Instructions for Use. 2009. N50 403; version 010. Data on file.